课程大纲Outline of the course |
章节 Section | 内容 Content | 学时 Hours |
1 | 绪论 | 4 |
| 1.1 What is cell biology | |
| 1.2 The cell theory | |
| 1.3 Cell is the basic unit of life | |
| 1.4 The prokaryotic cell | |
| 1.5 The eukaryotic cell | |
| 1.6 The technology of cell biology | |
2 | Chemical components of cells | 2 |
| 2.1 Chemical bonds | |
| 2.2 Organic molecules | |
3 | Biomembrane and cell surface | 4 |
| 3.1 Components and structure of biomembranes | |
| 3.2 Plasma membrane | |
| 3.3 Transmembrane transport | |
| 3.4 Cell junction and adhesion molecules | |
| 3.5 Extracellular matrix and cell wall | |
4 | Intracellular compartments and transport | 4 |
| 4.1 Organelles | |
| 4.2 Protein sorting inside cell | |
| 4.3 Molecular mechanisms of vesicular transport | |
| 4.4 Secretory pathways | |
| 4.5 Endocytic pathways | |
5 | Cytoskeleton | 4 |
| 5.1 Microtulules | |
| 5.2 Actin filaments | |
| 5.3 Intermediate filaments | |
6 | Signal transduction | 4 |
| 6.1 Signal molecules and their receptors | |
| 6.2 Functions of cell surface receptors | |
| 6.3 Signal network system | |
| 6.4 Cell signalling and the cytoskeleton | |
7 | Nucleus and chromosomes | 4 |
| 7.1 The nucleus of a eukaryotic cell | |
| 7.2 The nuclear envelope | |
| 7.3 Structure and role of the nuclear pore complex | |
| 7.4 Chromosomes and chromatin | |
| 7.5 Nucleolus and ribosome biogenesis | |
8 | Cell cycle and cell division | 2 |
| 8.1 An overview of the cell cycle | |
| 8.2 Regulation of the cell cycle | |
| 8.3 Cell division | |
9. | Cell differentiation | 4 |
| 9.1 Introduction | |
| 9.2 Cells with potency of differentiation | |
| 9.3 Stem cells | |
| 9.4 Epigenetic view of cell differentiation | |
10 | Cell senescence and apoptosis | 4 |
| 10.1 Senescence | |
| 10.2 Apoptosis | |
| 10.3 Senescence versus apoptosis | |
11 | Cancer cells | 4 |
| 11.1 Basic knowledge about cancer cell | |
| 11.2 Carcinogenesis | |
| 11.3 The genes involved in cancer | |
| 11.4 The genetic and epigenetic changes of cancer | |
| | |
| Experiments | |
| 1. Morphological observations of cell structures | 4 |
| 2. The observations of subcellular structures | 4 |
| 3. Cytological observation of mitosis | 4 |
| 4. Cell fusion | 4 |
| 5. Immunofluorescence staining of tumor cell skeleton | 4 |
| | |
| | |
合计 Total | | 60 |
