李敏，讲师，硕士生导师，生物化学教研室，邮箱：limin@ujs.edu.cn

主要从事基于噬菌体的致病菌临床诊断、噬菌体-宿主相互作用以及噬菌体源抗耐药菌活性物结构与功能方面的研究。

【学习工作经历】

2022.8-至今，江苏大学医学院，讲师

2018.9-2022.7，南京农业大学，预防兽医学，博士

2015.9-2018.7，扬州大学，微生物学，硕士

2010.9-2014.7，安徽科技学院，生物工程，本科

【教改科研项目】

中国博士后科学基金项目：肺炎克雷伯菌噬菌体宿主谱靶向拓宽及其抗CRKP作用研究，2023M731366，8万，主持。

江苏省自然科学基金：富集病毒微流控芯片制备及其呼吸道病毒检测应用研究，BK20230527，20万，参与。

江苏省重点研发计划（现代农业）项目：新型绿色噬菌体抗水禽致病菌制剂创制，BE2019304，40万，参与。

【代表性论文】

1. Li M, Wang H, Chen L, Guo G, Li P, Ma J, Chen R, Du H, Liu Y, Zhang W. Identification of a phage-derived depolymerase specific for KL47 capsule of Klebsiella pneumoniae and its therapeutic potential in mice [J]. Virologica Sinica, 2022, 37(4): 538-46.

2. Li M^#, Guo M^#, Chen L, Zhu C, Xiao Y, Li P, Guo H, Chen L^*, Zhang W^*, Du H^*. Isolation and characterization of novel lytic bacteriophages infecting epidemic Carbapenem-Resistant Klebsiella pneumoniae strains [J]. Frontiers in microbiology, 2020, 11: 1554. (^#共一, ^*共同通讯)

3．Li M, Shi D, Li Y, Xiao Y, Chen M, Chen L, Du H^*, Zhang W^*. Recombination of T4-like phages and its activity against pathogenic Escherichia coli in planktonic and biofilm forms [J]. Virologica Sinica, 2020, 35(5): 651-61. (^*共同通讯).

4. Li M, Li P, Chen L, Guo G, Xiao Y, Chen L, Du H, Zhang W. Identification of a phage-derived depolymerase specific for KL64 capsule of Klebsiella pneumoniae and its anti-biofilm effect [J]. Virus genes, 2021, 57(5): 434-42.

5. Li M, Xiao Y, Li P, Wang Z, Qi W, Qi Z, Chen L, Du H, Zhang W. Characterization and genome analysis of Klebsiella phage P509, with lytic activity against clinical carbapenem-resistant Klebsiella pneumoniae of the KL64 capsular type [J]. Archives of virology, 2020, 165(12): 2799-806.

6. Li M, Jelocnik M, Yang F, Gong J, Kaltenboeck B, Polkinghorne A, Feng Z, Pannekoek Y, Borel N, Song C, Jiang P, Li J, Zhang J, Wang Y, Wang J, Zhou X, Wang C. Asymptomatic infections with highly polymorphic Chlamydia suis are ubiquitous in pigs [J]. BMC veterinary research, 2017, 13(1): 370.

7. Li M, Zhang X, Huang K, Qiu H, Zhang J, Kang Y, Wang C. Presence of Chlamydia trachomatis and Mycoplasma spp., but not Neisseria gonorrhoeae and Treponema pallidum, in women undergoing an infertility evaluation: high prevalence of tetracycline resistance gene tet(M) [J]. AMB Express, 2017, 7(1): 206.

【获奖与专利】

授权发明专利：张炜，李敏，杜鸿，李培，肖宇屹；肺炎克雷伯氏菌噬菌株P560、噬菌体解聚酶Depo43及应用，2022-05-25，中国，CN202011451063.0。