陈盛霞,教授,博士生导师,寄生虫检验教研室,邮箱:chensxia@ujs.edu.cn
研究方向:病原体重要分子与宿主/细胞的相互作用、病原体分子生物学、生物分子与肿瘤
【学习工作经历】
1989年毕业于原镇江医学院检验专业并留校任教至今,2001年获苏州大学病原生物学硕士学位,2008年获江苏大学临床检验诊断学博士学位。
【科研项目】
主持“国家寄生虫资源库”/“科技部自然资源平台”、“十五科技攻关重大计划”和“十一五传染病重大专项”等子课题及市厅级以上课题共10余项,参加省级以上课题10余项。2017年至2021年底到账经费80余万元。共发表文章110余篇,其中SCI收录论文近20篇。
【代表性论文】
(1)Ahmad Daniyal Shahida, Ye Lu, Muhammad Asad Iqbala, Lin Lina, Shuang Huanga, Xugan Jianga, Shengxia Chen*. Listeria monocytogenes crosses blood brain barrier through Rho GTPases induced migration of macrophages and inflammatory interleukin expression[J]. Microbial Pathogenesis, 2021,159: 105143.
(2)Lin Yuan, Yurong Zhu, Shuang Huang, Lin Lin, Xugan Jiang, Shengxia Chen*. NF-κB/ROS and ERK pathways regulate NLRP3 inflammasome activation in Listeria monocytogenes infected BV2 microglia cells[J]. J Microbiol, 2021, 59(8):771-781.
(3)Yurong Zhu, Ye Lu, Lin Yuan, Wei Ling, Xugan Jiang, Shengxia Chen*, Bing Hu*. LincRNA-Cox2 regulates IL6/JAK3/STAT3 and NF-κB P65 pathway activation in Listeria monocytogenes-infected RAW264.7 cells[J]. Int J Med Microbiol, 2021, 311(5):151515.
(4)Liang Wu, Lipei Wu, Chenyu Tang, Jiajian Wang, Xiaoling Jin, Xugan Jiang, Shengxia Chen*. Induction of FAS II Metabolic Disorders to Cause Delayed Death of Toxoplasma gondii[J]. Journal of Nanoscience and Nanotechnology. 2018,18(12):8155–8159.
(5)Haiqiang Jiang, Huiyun Wang, Fengyuan Ge, Lamei Wu, Xiao Wang, Shengxia Chen*. The
Functional Variant in the 3’UTR of IGF1 with the Risk of Gastric Cancer in a Chinese
Population[J]. Cellular Physiology and Biochemistry, 2015, 36(3): 884-892.
(6)Liang Wu,Jin Shen,Yupei Zhou,Xiao Wang,Lamei Wu,Xugan Jiang,Shengxia Chen*.
Toxoplasma gondii nucleus coding apicoplast protein ACP synthesis and trafficking in
delayed death[J]. Parasitology Research. 2015, 114(3):1099-1105.
(7)Liang Wu, Xu-gan Jiang, Yu-juan Shen, Zhao-xi Lu, Guo-hua Tu, Xing-li Fu, Sheng-xia Chen* and Jian-ping Cao. Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture [J].Parasitology Research. 2011, 109(5):1474-1479.
(8)Liang Wu, Sheng-Xia Chen*, Xu-Gan Jiang, Jian-Ping Cao. Toxoplasma gondii: a simple Real-time PCR assay to quantify the proliferation of the apicoplast[J]. Experimental Parasitology. 2009, 123(4): 384-387.
(9)Sheng-Xia Chen, Liang Wu, Xu-Gan Jiang, Yao-Yu Feng, Jian-Ping Cao. Anti-Toxoplasma gondii activity of GAS in vitro[J]. Journal of Ethnopharmacology. 2008, 118 (3):503–507.
(10)CHEN Sheng-Xia, WU Liang, YANG Xiao-Ming, JIANG Xu-Gan, LI Long-Gen, ZHANG Rong-Xian, Xia Lei and SHAO Shi-He. Comparative molluscicidal action of extract of Ginko biloba sarcotesta , arecoline and niclosamide on snail hosts of Schistosoma japonicum[J].
Pesticide Biochemistry and Physiology.2007, 89(3):237-241.
【教材与专著】
共参加40余本教材和论著的编写,其中主编3本,副主编2本,
【获奖与专利】
获上海市科技进步一等奖和镇江市科技进步三等奖各1项,获授权专利4项。