陈燕燕，讲师，药理教研室，邮箱：yanyanchan@126.com

【学习工作经历】

2023.1-至今 澳门大学 澳门青年学者

2022.12-至今 江苏大学 博士后

2021.1-至今 江苏大学 讲师

2019.9-2020.9 中山大学 研究人员

【教改科研项目】

获得2022年度中国博士后国（境）外交流项目“澳门青年学者计划”，72万元资助

【代表性论文】

[1] Yan-Yan Chen, Fei Fei, Ling-Ling Ding, Shi-Yuan Wen, Cai-Fang Rena, Ai-Hua Gong*. Integrated gut microbiome and metabolome analysis reveals the inhibition effect of Lactobacillus plantarum CBT against colorectal cancer. Food Funct. 2024, 15, 853-865.

[2] Shi-Yuan Wen, Xiao-Yan Zhi, Hai-Xin Liu, Xiao-Hui Wang, Yan-Yan Chen*, Li Wang*. Is the suppression of CD36 a promising way for atherosclerosis therapy? Biochem Pharmacol. 2024, 219, 115965.

[3] Yang Wang ^#, Yan-Yan Chen ^#, Gui-Bin Gao ^#, Yang-Han Zheng , Nan-Nan Yu , Lan Ouyang , Xuejuan Gao , Nan Li , Shi-Yuan Wen , Shangjia Huang , Qian Zhao, Langxia Liu, Mingrong Cao, Shuixing Zhan, Jing Zhang, Qing-Yu He^*. Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase, Mol Ther, 2023, 31, 2169-2187.

[4] Shi-Yuan Wen*, Bing-Yan Wei, Jie-Qiong Ma, Li Wang*, Yan-Yan Chen*. Phytochemicals, Biological Activities, Molecular Mechanisms, and Future Prospects of Plantago asiatica L. J Agric Food Chem, 2023, 71, 143-173.

[5] Shi-Yuan Wen*, Yan-Tong Liu, Bing-Yan Wei, Jie-Qiong Ma, Yan-Yan Chen*. PDCD6 Promotes Hepatocellular Carcinoma Cell Proliferation and Metastasis through the AKT/GSK3β/β-catenin Pathway. Biomed Environ Sci, 2023, 36, 241-252.

[6] Yan-Yan Chen*, Cai-Fang Ren, Shi-Yuan Wen*. Polyphyllin D induces G2/M Cell Cycle Arrest via Dysfunction of Cholesterol Biosynthesis in Liver Cancer Cells. Biomed Environ Sci, 2023, 36, 94-98.

[7] Shi-Yuan Wen^#, Yan-Yan Chen^#, Jia-Xi Lu, Qian-Qian Liang, Hong Shi, Qian Wu, Zhi-Hong Yao, Yan Zhu, Miao-Miao Jiang*. Modulation of hepatic lipidome by rhodioloside in high-fat diet fed apolipoprotein E knockout mice. Phytomedicine, 2020, 69, 152690.

[8] Yan-Yan Chen^#, Shi-Yuan Wen^#, Chun-Miao Deng, Xin-Feng Yin, Zheng-Hua Sun, Miao-Miao Jiang*, Qing-Yu He*. Proteomic analysis reveals that Odoroside A triggers G2/M arrest and apoptosis in colorectal carcinoma through ROS-p53 pathway. Proteomics, 2019, 19(15): e1900092.

[9] Shi-Yuan Wen^#, Yan-Yan Chen^#, Chun-Miao Deng, Cui-Qiong Zhang, Miao-Miao Jiang*. Nerigoside suppresses colorectal cancer cell growth and metastatic potential through inhibition of ERK/GSK3β/β-catenin signaling pathway. Phytomedicine, 2019, 57, 352-363.

[10] Yan-Yan Chen^#, Shi-Yuan Wen^#, Miao-Miao Jiang*, Yan Zhu, Li-Qin Ding, Hong Shi, Peng-Zhi Dong, Jing Yang, Yue Yang. Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE^-/- mice fed with a high-fat diet. Atherosclerosis, 2017, 262: 76-86.

【获奖与专利】

姜苗苗;王跃飞;陈燕燕;李晓男;一种黄芪注射液初生代谢成分的含量检测方法, 2017-01-18,中国, CN104698021B.