丁伶伶，资格教授，硕士生导师，生理学教研室，邮箱：l.ding@ujs.edu.cn

【研究方向】

代谢性疾病如肥胖，糖尿病，非酒精性脂肪肝的早期诊断，发病机制及药物靶点的研究

【学习工作经历】

2021年12月-至今：江苏大学医学院 生理教研室

2017年9月-2021年5月：荷兰马斯特里赫特大学医学院获得博士学位

2016年7月-2017年8月：北京凯因科技股份有限公司药物研究院

2013年9月-2016年6月：天津中医药大学获得药剂学硕士学位

2009年9月-2013年7月：新乡医学院获得医学学士学位

【教改科研项目】

江苏大学高层次人才科研启动经费（5501280008），28万，主持

【代表性论文】

1.Lingling Ding, Toon. J. I. De Munck, Yvonne Oligschlaeger, Jef Verbeek, Ger. H. Koek, Tom Houben, Ronit Shiri Sverdlov. Insulin resistance is positively associated with plasma cathepsin D activity in NAFLD patients. Biomolecular Concepts, August 2021; 12: 110–115.

2.Lingling Ding, Toon. J. I. De Munck, Yvonne Oligschlaeger, Inês Magro dos Reis, Jef Verbeek, Ger. H. Koek, Tom Houben, Ronit Shiri-Sverdlov. Myosteatosis in NAFLD patients correlates with plasma Cathepsin D. Biomolecular Concepts, 2021 May 15;12(1):27-35.

3.Lingling Ding, Tom Houben, Yvonne Oligschlaeger, Albert V. Bitorina, Bart Verwer, Maarten E. Tushuizen & Ronit Shiri-Sverdlov. Plasma Cathepsin D activity rather than levels correlates with metabolic parameters of type 2 diabetes in male individuals. (2020) Frontiers in Endocrinology. 11, 776.

4.Lingling Ding, Gijs H. Goossens，Yvonne Oligschlaeger, Tom Houben, Ellen E. Blaak & Ronit Shiri Sverdlov. Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans. Diabetologia 63, 374–384 (2020)

5.Lingling Ding, Jiawei Li, Rui Huang, Zhidong Liu, Chunhua Li, Shaozi Yao, Jinyan Wang, Dongli Qi, Nan Li, Jiaxin Pi. Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO2; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO2 nanoparticles, International Journal of Nanomedicine, 2016:11 5709–5727 (2019 impact factor: 5.115)

6.Lingling Ding, Zhidong Liu, Mike Okweesi Aggrey, Chunhua Li, Jing Chen and Ling Tong. Nanotoxicity: The Toxicity Research Progress of Metal and Metal-Containing Nanoparticles, Mini-Reviews in Medicinal Chemistry, 2015, 15, 529-542. (2019 Impact factor:2.733)

7.Albert V Bitorina, Yvonne Oligschlaeger, Lingling Ding, Tulasi Yadati, Annemary Westheim, Tom Houben, Rianne DW Vaes, Steven WM Olde Damink, Jan Theys, Ronit Shiri-Sverdlov. OxLDL as an Inducer of a Metabolic Shift in Cancer Cells. J Cancer. 2021 Aug 3;12(19):5817-5824.

8.Zhidong Liu#, Qian Zhang#, Lingling Ding, Chunhua Li, Zhongpeng Yin, Guoqiang Yan, Jiaxin Pi, Jiawei Li, Nan Li, Dongli Qi. Preparation procedure and pharmacokinetic study of water-in-oil nanoemulsion of Panax notoginseng saponins for improving the oral bioavailability, Current Drug Delivery, 2015, June 7.

9.Chunhua Li, Songlin Xu, Zhidong Liu, Lingling Ding, Xiaobin Zhao, Robert J Lee . (2016). Evaluation of a Non-aqueous Ibuprofen-Phospholipid Complex Formulation in Rats. In vivo (Athens, Greece), 30(4), 479–483.

10.Kati Mokkala, Johanna Gustafsson, Tero Vahlberg, Anita C E Vreugdenhil, Lingling Ding, Ronit Shiri-Sverdlov, Jogchum Plat, Kirsi Laitinen (2022). Serum CathepsinD in pregnancy: Relation with metabolic and inflammatory markers and effects of fish oils and probiotics. Nutrition, metabolism, and cardiovascular diseases : NMCD, 32(5), 1292–1300.

【教材与专著】

Lingling Ding, Yvonne Oligschlaeger, Ronit Shiri-Sverdlov, Tom Houben. Nonalcoholic Fatty Liver Disease. 2020 Mar 18. In: von Eckardstein A, Binder CJ, editors. Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art Management and Search for Novel Targets [Internet]. Cham (CH): Springer; 2022;270:233-269.

【荣誉与兼职】

2022年度江苏大学优秀学业导师

2022年江苏省“双创博士” （JSSCBS20221179）