Date of Birth
1965
Research Area
The major theme of my research has focused on the regulatory roles of regulatory T cells, dendritic cells and microRNA and using these for anti-tumor, anti-autoimmunity and anti-rejection therapy. About 90 papers were published. The research work was supported by National Nature Science Foundation of China, Jiangsu Government and 973 Grant of National Government.
Primary Course
Professinal Education
Deputy & Professor,
Department of Immunology,
School of Medical Science and Laboratory Medicine,
Jiangsu University,
301 Xuefu Road, Zhenjiang 212013, Jiangsu, P. R. China
Education/Training
M.D., Nanjing Medical University, Medicine, 1987.6
M.S., Tonji Medical College of Huazhong University of Science and Technology, Immunology, 1999.6
Ph.D., Peking University Health Science Center, Immunology, 2005.7
Academic Introduction
Research and Professional Experience
1987-1992
Lecturer, Department of Microbiology & Immunology, Zhenjiang Medical College.
1992-1999
Assistant Professor, Department of Immunology, Zhenjiang Medical College.
1999-2005
Associate Professor, Department of Immunology, School of Medical Science and Laboratory Medicine, Jiangsu University.
2005-present
Professor, Department of Immunology, School of Medical Science and Laboratory Medicine, Jiangsu University.
Scientific Research Item and Achievement
The Standing Committee and Vice General Secretary of The Society of Immunology of Jiangsu Province(2005); The Commissioner of Youth Academic Committee of Chinese Society of Immunology(2004); Member, Chinese Society of Immunology(1999); Member, Chinese Society of Microbiology(1999)
Publications
Recently major publications
1.Huang Y, Li R, Chen X, Zhuo Y, Jin R, Qian XP, Jiang YQ, Zeng ZH, Zhang Y, Shao QX (Correspondence author). Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-?B pathways in mouse thymic epithelial cells. Int Immunopharmacol. 2011 Sep;11(9):1143-9.
2.Tian J, Ma J, Wang S, Yan J, Chen J, Tong J, Wu C, Liu Y, Ma B, Mao C, Jiao Z, Shao Q, Lu L, Xu H. Increased expression of mGITRL on D2SC/1 cells by particulate ?-glucan impairs the suppressive effect of CD4+CD25+ regulatory T cells and enhances the effector T cell proliferation. Cell Immunol. 2011;270(2):183-7.
3.Chen X, Xia S, Li R, Liu H, Huang Y, Qian X, Xiao X, Xu X, Lin X, Tian Y, Zong Y, He D, Chen W, Zhang Y, Shao Q (Correspondence author). Doxycycline enhances the Ras-MAPK signaling and proliferation of mouse thymic epithelial cells. J Cell Biochem. 2009;107(3):494-503.
4.Mao C, Wang S, Jiang Q, Tong J, Ma J, Yang M, Xu X, Qiu G, Shao Q, Li L, Xu H. Increased CD4CD25+FOXP3+ regulatory T Cells in cancer patients from conversion of CD4+CD25- T cells through tumor-derived factors. Onkologie. 2008 May;31(5):243-8.
5.Yang M, Wang S, Wang S, Ma J, Xu X, Mao C, Ma B, Tong J, Qiu G, Shao Q, Ding Q, Xu H. Tat-mediated intracellular delivery of T-bet protein into THP-1 cells can induce Th1-type response. Immunol Invest. 2008;37(2):97-111.
6.Wang S, Xu H, Wang Y, Ma J, Mao C, Shao Q, Ma B, Xu W, Yang S. Regulatory T cells inducedd by rAAV carrying the forkhead box P3 gene prevent autoimmune thyroiditis in mice. Int J Mol Med. 2006 Dec;18(6):1193-9.
7.Naik SH, Proietto AI, Wilson NS, Dakic A, Schnorrer P, Fuchsberger M, Lahoud MH, O'Keeffe M, Shao QX, Chen WF, Villadangos JA, Shortman K, Wu L. Cutting edge: generation of splenic CD8+ and CD8- dendritic cell equivalents in Fms-like tyrosine kinase 3 ligand bone marrow cultures. J Immunol. 2005;174(11):6592-6597.
8.Dakic A, Shao QX, D'Amico A, O'Keeffe M, Chen WF, Shortman K, Wu L. Development of the dendritic cell system during mouse ontogeny. J Immunol. 2004;172(2):1018-27.
