Date of Birth
1970

Research Area
1.Mesenchymal stem cells transplantation in injury diseases,2.Mesenchymal stem cells and tumorigenesis,3.Stem cell correlation factor detection and clinic application

Primary Course

Professinal Education
Personal Information：
Name: Hui Qian, Ph.D.,
Date of Birth: Oct, 1970
Department: Cellular and Molecular Diagnostics
Division: School of Medical Science and Laboratory Medicine
Business Address: Jiangsu University,
School of Medical Science and Laboratory Medicine,
Department of Cellular and Molecular Diagnostics
301Xuefu Road, Zhenjiang, Jiangsu 212013, P. R. China
Business Telephone: (+86) 511-85038334
Business FAX: (+86) 511-85038483
E-mail: lstmmmlst@163.com

Academic Introduction
Education：
Sep,2004-Jun, 2006, Ph.D. in genetics, Shanghai Jiao Tong University, P.R.China.
Sep,1997-Jun, 2000, Master in biochemistry and Molecular Biology, Xuzhou Medical University, P.R.China.
Sep,1988-Jun, 1992, Bachelor in biology, Nanjing Normal University, P.R.China. Major in cell biology.

Work Experience:
Jul,1992-Aug,1998 Teaching Assistant. Biochemistry, Zhenjiang Medical School
Sep,1998- Mar, 2001 Lecturer. Zhenjiang Medical School
Apr,2001- Jul, 2005 Lecturer. Associate director of department of Biochemistry and Clinical Biochemistry, Jiangsu University
Aug, 2005- Jul, 2011 Associated Professor. Director of department of cellular and molecular diagnostics, Jiangsu University
Aug, 2011-present Professor. Director of department of cellular and molecular diagnostics, Jiangsu University

Major Research Interests：
 Mesenchymal stem cells transplantation in injury diseases
 Mesenchymal stem cells and tumorigenesis
 Stem cell correlation factor detection and clinic application

Scientific Research Item and Achievement
Awards and Group Memberships：
2009, trans-century Academic Leader of Common Colleges and Universities in Jiangsu Province (333 Projects)
2008, Second Nature Science Prize in Chinese Universities, Ministry of Education, Rank 2.
2008, Third Prize of Science and Technology Progress in Jiangsu Province, Rank 2.
2007, First Nature Science Prize in Chinese Universities, Ministry of Education, Rank 5.

Publications
Publications:
1 Qian H, Yang H, Xu W, Yan Y, Chen Q, Zhu W, Cao H, Yin Q, Zhou H, Mao F, Chen Y. Bone marrow mesenchymal stem cells ameliorate rat acute renal failure by differentiation into renal tubular epithelial-like cells. Int J Mol Med, 2008, 22: 325-332.
2Qian H, Wang J, Wang S, Gong Z, Chen M, Ren Z, Huang S. In utero transplantation of human hematopoietic stem/ progenitor cells partially repairs injured liver in mice. Int J Mol Med, 2006, 18(4): 633-642.
3 Qian H, Zhang X, Xu W, Zhu W, Cao H, Chen Y, Xu X, Wang M, Xie Y, Sun J. Lentivirus-modified human umbilical cord mesenchymal stem cells maintain their pluripotency. Biotechnol Appl Biochem, 2010, 55(1): 53-62.
4Xu X, Qian H?co-author?, Zhu W, Zhang X, Xu W. Isolation of cancer stem cells from transformed human mesenchymal stem cell line F6. J Mol Med, 2010, 88(11): 1181-1190.
5Chen Y, Qian H(Corresponding Author), Zhu W, Zhang X, Yan Y, Ye S, Peng X, Li W, Xu W. Hepatocyte growth factor modification promotes the amelioration effects of human umbilical cord mesenchymal stem cells on rat acute kidney injury. Stem Cell Dev, 2011, 20(1):103-113.
6 Qian Q, Qian H?co-author?, Zhang X, Zhu W, Yan Y, Ye S, Peng X, Li W, Xu Z, Sun L, Xu W. 5-Azacytidine induces cardiac differentiation of human umbilical cord derived mesenchymal stem cells by activating extracellular regulated kinase?ERK?. Stem Cells Dev, 2011 Apr 8 [Epub ahead of print].
7Cao H, Qian H?co-author?, Xu W, Zhu W, Zhang X, Chen Y, Wang M, Yan Y, Xie Y. Mesenchymal stem cells derived from human umbilical cord ameliorate ischemia/reperfusion-induced acute renal failure in rats. Biotechnol Lett, 2010, 32(5):725-732.
8Xu W, Qian H, Zhu W, Chen Y, Shao Q, Sun X, Hu J, Han C, Zhang X. A novel tumor cell line cloned from mutated human embryonic bone marrow mesenchymal stem cells. Oncol Rep, 2004, 12: 501-508.
9Zhang X, Xu W, Qian H , Zhu W, Zhang R. Mesenchymal stem cells modified to express lentivirus-TNFalpha- Tumstatin inhibit the growth of prostate cancer. J Cell Mol Med, 2011, 15(2): 433-444.
10Cao H, Xu W, Qian H, Zhu W, Yan Y, Zhou H, Zhang X, Xu X, Li J, Chen Z, Xu X. Mesenchymal stem cell-like cells derived from human gastric cancer. Cancer lett, 2009, 274(1):61-71.
11Zhou H, Xu W, Qian H, Yin Q, Zhu W, Yan Y. Circulating RNA as a novel tumor marker: An in vitro study of the origins and characteristics of extracellular RNA. Cancer lett, 2008, 259(1): 50–60.
12Yan Y, Xu W, Qian H, Si Y, Zhu W, Cao H, Zhou H, Mao F. Mesenchymal stem cells from human umbilical cords ameliorate mouse hepatic injury in vivo. Liver Int, 2009,29(3): 356-365.
13Chen Z, Xu W, Qian H, Zhu W, Bu X, Wang S, Yan Y, Mao F, Gu H, Cao H, Xu X. Oct4, a novel marker for human gastric cancer. J Surg Oncol, 2009, 99(7): 414-419.
14Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, Zhou H, Chen Y. Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro. Exp Bio Med, 2004, 229: 623-631.
15Sun X, Cai H, Qian H, Zhu W, Yan Y, Xu H, Xu W. Mesenchymal stem cells isolated from human uterine cervix cancer tissues. Cell Biol Int, 2010, 35(2):119-223.
16Mao F, Xu W, Qian H, Zhu W, Yan Y, Shao Q, Xu H. Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis. Inflamm Res, 2010, 59(3): 219-225.
17Yan Y, Hao S, Qian H, Fei R, Xu W. Expression and detection of human phosphodiesterase 3B gene in baculovirus. Acta pharmacologica sinaca, 2006, 27 (Suppl): 247-247.
18Yan Y, Xu W, Qian H, Zhu W, Mao F, Zhang X. Tumstatin45-132-TNF alpha suppresses tumour growth through anti-angiogenic effects and cytotoxicity. Biotechnol Appl Biochem, 2010, 56(3):119-127.
19Xu W, Zhou H, Qian H, Bu X,Chen D, Gu H, Zhu W, Yan Y, Mao F. Combination of circulating CXCR4 and Bmi-1 mRNA in plasma: A potential novel tumor marker for gastric cancer. Mol Med Rep, 2009, 2: 765-771.
20Zhu W, Huang L, Li Y, Qian H, Shan X, Yan Y, Mao F, Wu X, Xu W. Mesenchymal stem cell-secreted soluble signaling molecules potentiate tumor growth. Cell Cycle, 2011 Sep 15;10(18). [Epub ahead of print]
21Xu X, Zhang X, Wang S, Qian H, Zhu W, Cao H, Wang M, Chen Y, Xu W. Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues. J Cancer Res Clin Oncol, 2011, 137(3) : 495-504.
22Zhu W, Huang L, Xu X, Qian H, Xu W. Anti-proliferation effect of BMI-1 in U937 cells with siRNA. Int J Mol Med, 2010, 25(6):889-895.
23Zhu W, Xu W, Jiang R, Qian H, Chen M, Hu J, Cao W, Han C, Chen Y. Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo. Exp Mol Pathol, 2006, 80(3): 267-274.
24Han C, Zhang X, Xu W?Wang W, Qian H, Chen Y. Cloning of nucleostemin gene and its function in transforming human embryonic bone marrow mesenchymal stem cells into F6 tumor cells. Int J Mol Med, 2005, 16(2): 205-213.
25Qiao C, Xu W, Zhu W, Hu J, Qian H, Yin Q, Jiang R, Yan Y, Mao F, Yang H, Wang X, Chen Y. Human mesenchymal stem cells isolated from the umbilical cord. Cell Biol Int, 2008, 32(1): 8-15.
26Jiang R, Xu W, Zhu W, Chen M, Qian H, Qiao C, Yang H, Wang X, Chen Y. Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells. Oncol Rep, 2006, 16(5):1021-1028.
27Zeng F, Chen M, Baldwin DA, Gong Z, Yan J, Qian H, Wang J, Jiang X, Ren Z, Sun D, Huang S. Multiorgan engraftment and differentiation of human cord blood CD34+lin- cell in goats assessed by gene expression profiling. Proc Natl Acad Sci U S A, 2006, 103(20): 7801-7806.
28Zeng F, Chen M, Katsumata M, Huang W, Gong Z, Hu W, Qian H, Xiao Y, Ren Z, Huang S. Identification and characterization of engrafted human cells in human/goat xenogeneic transplantation chimerism. DNA and cell biology, 2005, 24(7): 403- 409.