Date of Birth
1963.06

Research Area

Primary Course
1.Biochemistry and Molecular Biology to Medical students;2.Research and Technology of Molecular Biological to Master graduate student;3.Advance Molecular Biological Technology to Ph.D. student.

Professinal Education
Xinxiang Huang, M.D. & Ph.D., Professor of Department of Biochemistry and Molecular Biology; Master and Doctoral Instructor in Medical Technology and Laboratory Diagnosis.

Education experience:

1.From Sep/1980 to Jul/1985, studied in Suzhou University as a medical student in Clinical Medicine;
2.From Sep/1988 to Jul/1991, studied in Daliang Medical University as a master graduate student student in Biochemistry;
3.From Apr/2001 to Jul/2004, studied in Gifu University (Japan) as a Ph.D. student in Medical Science;

Work experience:

1.From Jul/1985 to Mar/2000, worked in Zhenjiang Medical College as assistant/associate professor in Clinical Biochemistry;
2.From Jul/2004 to now, working in Jiangsu University School of Medical Technology as professor in Biochemistry and Molecular Biology.

Academic Introduction
Scientific research:
1.DNA microarray and gene expressional regulation of Salmonella;
2.Infection of Salmonella and immunity
3.Molecular diagnosis of infectious diseases.

Scientific Research Item and Achievement
Instruction courses:
1.Biochemistry and Molecular Biology to Medical students;
2.Research and Technology of Molecular Biological to Master graduate student;
3.Advance Molecular Biological Technology to Ph.D. student.

Social position:
1.A director of Jiangsu Committee of Biochemistry and Molecular Biology;
2.A director of Committee of Analysis Microbiology, Chinese Society for Microbiology

Publications
Recent Publications:
1.Wang M, Luo Z, Du H, Xu S, Ni B, Zhang H, Sheng X, Xu H, Huang X*. Molecular character ization of a functional type VI secretion system in Salmonella enterica serovar Typhi. Curr Microbiol. 2011, 63: 22-31.
2.Du H, Wang M, Luo Z, Ni B, Wang F, Meng Y, Xu S, Huang X*. Coregulation of Gene Expression by Sigma Factors RpoE and RpoS in Salmonella enterica Serovar Typhi During Hyperosmotic Stress. Curr Microbiol. 2011, 62:1483–1489.
3.Luo Z; Wang M; Du H, Yang T, Wang F, Ni B, Xu S, Huang X*. The putative sensor kinase QseC of Salmonella enterica serovar Typhi can promote invasion in the presence of glucose. Food Research International. 2011. (DOI: 10.1016/j.foodres.2011.01.019).
4.Du H, Sheng X, Zhang H, Ni B, Zhu X, Xu H, Huang X*. RpoE may promote flagellar gene expression in Salmonella enterica serovar Typhi under hyperosmotic stress. Curr Microbiol. 2011, 62: 492–500.
5.Gao H, Zhang Y, Han Y, Yang L, Liu X, Guo Z, Tan Y, Huang X, Zhou D, Yang R*. Phenotypic and transcriptional analysis of the osmotic regulator OmpR in Yersinia pestis. BMC Microbiol. 2011, 11: 39.
6.Gao H, Zhang Y, Yang L, Liu X, Guo Z, Tan Y, Han Y, Huang X, Zhou D, Yang R *. Regulatory effects of cAMP receptor protein (CRP) on porin genes and its own gene in Yersinia pestis.. BMC Microbiol. 2011, 11: 40.
7.Xie X, Li A, Du H, Sheng X, Zhang H, Xu S, Huang X*. Expression of tviA is transiently repressed by Hfq in Salmonella enterica serovar Typhi at hyperosmotic stress. Microbial Pathog. 2010, 49: 54-57.
8.Xu S, Zou X, Sheng X, Zhang H, Mao L, Du H, Xu H, Huang X*. Expression of fljB:z66 on a linear plasmid of Salmonella enterica serovar Typhi is dependent on FliA and FlhDC and regulated by OmpR. Br J Microbiol. 2010, 41: 729-740.
9.Zhang H, Sheng X, Xu S, Gao Y, Du H, Li J, Xu H, Huang X*. Global transcriptional response of Salmonella enterica serovar Typhi to anti-z66 antiserum. FEMS Microbiol Lett. 2009, 298: 51-5.
10.Zou X, Huang X* , Xu S, Zhou L, Sheng X, Zhang H, Xu H, Ezaki T. Identification of a fljA gene on a linear plasmid as the repressor gene of fliC in Salmonella enterica serovar Typhi. Microbiol Immunol. 2009, 53: 191-197.
11.Sheng X, Huang X*, Mao L, Zhu C, Xu S, Zhang H, Xu H, Liu X. Preparation of genomic DNA microarray of Salmonella enterica serovar Typhi for gene expression profile analysis. Prog Biochem Biophs. 2009, 36: 206-212.
12.Sheng X, Huang X*, Li J, Xie X, Xu S, Zhang H, Xu H. Regulation of Sulfur Assimilation Pathways in Salmonella enterica Serovar Typhi Upon Up-Shift High Osmotic Treatment: The Role of UhpA Revealed Through Transcriptome Profiling. Curr Microbiol. 2009, 59: 628-635.
13.Xu S, Zhang H, Sheng X, Xu H, Huang X*. Transcriptional expression of fljB:z66, a flagellin gene located on a novel linear plasmid of Salmonella enterica serovar Typhi under environmental stresses. New Microbiol. 2008, 31: 241-247.
14.Huang X, Xu H, Sun X, Ohkusu K, Kawamura Y, and Ezaki T. Genome-wide scan of the gene expression kinetics of Salmonella enterica serovar Typhi during hyperosmotic stress. Int J Mol Sci. 2007, 8: 116-135.
15.Xu S, Huang X, Zhang C. Improved prediction of coreceptor usage and phenotype of HIV-1 based on combined features of V3 loop sequence using random forest. J Microbiol. 2007, 45: 441-446.
16.Huang X, Xu H, Sha MM, Zhao L, Ohkusu K, Kawamura Y, Ezaki T. Virulence-defective strains of Salmonella enterica serovar Typhi as candidates for education at level 2 facilities. Microbiol Immunol. 2006, 50: 273-279.