Date of Birth

Research Area
1. Functions of apicoplast in apicomplexa parasites, especially in Toxoplasma gondii. gondii. 3. Infection and immunity.

Primary Course

Professinal Education
Dr. Sheng-Xia Chen, Professor
School of Medical Science and Laboratory Medicine
Jinagsu University, Zhenjiang, 212013 P. R. China
Phone: 86-511-85038965-324
Fax: 86-511-85038483

PROFESSIONAL EDUCATION
Degree Awarding Institution Field of Study Year of Graduation
Ph. D. Jiangsu University Clinical Laboratory Diagnostics 2008
M. Sc. Suzhou University Pathogenic Biology 2001
B. Sc. Zhenjiang Medical College Laboratory Medicine 1989

Academic Introduction
RESEARCH INTERESTS
Study on the molecular pathogenic mechanism, diagnostic and therapeutic methods, and immunologic mechanism of parasitic diseases.
The major areas where the group is currently working are:
1. Functions of apicoplast in apicomplexa parasites, especially in Toxoplasma gondii.
2. Molecular diagnostic methods for the opportunistic parasitic diseases.
3. Infection and immunity.

Scientific Research Item and Achievement

Publications
PUBLICATIONS (Selected)
1. Sheng-Xia Chen, Liang Wu, Xu-Gan Jiang, Yao-Yu Feng, Jian-Ping Cao. Anti-Toxoplasma gondii activity of GAS in vitro[J]. Journal of Ethnopharmacology. 2008, 118(3):503–507. ?SCI?
2. Chen Sheng-Xia, Wu Liang, Yang Xiao-Ming, Jiang Xu-Gan, Li Long-Gen, Zhang Rong-Xian, Xia Lei, Shao Shi-He. Comparative molluscicidal action of extract of Ginko biloba sarcotesta, arecoline and niclosamide on snail hosts of Schistosoma japonicum[J]. Pesticide Biochemistry and Physiology.2007, 89:237-241.?SCI?
3. Liang Wu, Xu-gan Jiang, Yu-juan Shen, Zhao-xi Lu, Guo-hua Tu, Xing-li Fu, Sheng-xia Chen*, Jian-ping Cao. Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture[J]. Parasitology Research. Online First™, 10 May 2011. ?SCI?
4. Liang Wu, Sheng-xia Chen*, Xu-gan Jiang, Xing-li Fu, Yu-juan Shen, Jian-ping Cao. Separation and purification of Toxoplasma gondii tachyzoites from in vitro and in vivo culture systems. Experimental Parasitology. Available online 15 October 2011. ?SCI?
5. Liang Wu, Sheng-xia Chen*, Xu-gan Jiang, Yu-juan Shen, Zhao-xi Lu, Guo-hua Tu, Xing-li Fu, Jian-ping Cao. Effect of select medium supplements on in vitro development of Cryptosporidium andersoni in HCT-8 cells[J]. Parasitology Research. 2009, 105(5): 1419-1424. ?SCI?
6. Liang Wu, Sheng-Xia Chen*, Xu-Gan Jiang, Jian-Ping Cao. Toxoplasma gondii: a simple Real-time PCR assay to quantify the proliferation of the apicoplast[J]. Experimental Parasitology. 2009, 103(4): 384-387.?SCI?
7. Xiao-ming Yang, Sheng-xia Chen, Lei Xia, Jun Chen. Molluscicidal activity against Oncomelania hupensis of Ginkgo biloba[J]. Fitoterapia. 2008, 79: 250–254.?SCI ?
8. CHEN Sheng-xia?WU Liang?SHEN Yu-juan?ZHANG Qiu-xia?LI Ting-ting?JIANG Xu-gan?XU Yu-xin?CAO Jian-ping. Comparison of the Effects on Extraction of Cryptosporidium Oocyst DNA by Different Methods Using
Real-time PCR[J]. Chinese Journal of Parasitology and Parasitic Diseases. 2009, 27(2):130-134. (in Chinese)
9. Chen SX, Wu L, Yang XM, Jiang XG, Li LG, Zang RX, Xia L, Shao SH. Lethal Effects of Extracts of Ginkgo biloba Sarcotesta upon the Snail Oncomelania hupensis[J]. Acta Zoologica Sinica. 2007, 53(1):190-194. (in Chinese)
10. Chen SX, Yang XM, Wu L, Li LG, Zhang RX, Xia L, Shao SH. Study on Molluscicidal Effect of the Extracts from Sarcotesta of Ginkgo biloba[J]. Chinese Journal of Parasitology and Parasitic Diseases. 2007,25(1):45-48. (in Chinese)
11. Chen SX, Yang XM, Zhang RX, Li LG, Wu L, Shao SH. Study on Molluscidal Effects of Extracts from Sarcotesta of
Ginkgo biloba Combined with Arecoline[J]. Journal of Jiangsu University (Medicine Edition). 2007, 17(1):1-4. (in Chinese)
12. LU Zhao-xi, WU Liang, JIANG Xu-gan, SHEN Yu-juan, FU Xing-li, TU Guo-hua, LI Li, CHEN Sheng-xia*, CAO Jian-ping. In vitro proliferation of Cryptosporidium andersoni in HCT-8 and AGS cell lines[J]. Chinese Journal of Zoonoses. 2011,27(6):475-479. (in Chinese)
13. WU Liang?ZHANG Qiu-xia?LI Ting-ting?CHEN Sheng-xia*?CAO Jian-ping. Cultivation of Toxoplasma gondii RH Strain Tachyzoites in HFF and HeLa Cells[J]. Chinese Journal of Parasitology and Parasitic Diseases. 2009, 27(3):229-231. (in Chinese)
14. WU Liang, CHEN Sheng-xia*, LI Lin-jie, CHE Fei-hu, DENG Hong-yan, JIANG Xu-gan. Observation on the Culture of RH Strain Tachyzoite of Toxoplasma gondii in HeLa cells[J]. Chinese Journal of Parasitology and Parasitic Diseases.2008, 26(6): 452-456. (in Chinese)
15. WU Liang, CHEN Sheng-xia*, JIANG Xu-gan, ZHOU Tian-ji, XU Hui-juan, SHUAI Lian-yu, FU Xing-li, CAO Jian-ping. Study on the anti-Toxoplasma activity of ginkgolic acids, azithromycin and allicin[J]. Chinese Journal of Zoonoses. 2008,24(8):736-740. (in Chinese)