主要论著
已发表的部分代表性学术论文: 1. Lin, Q., Wang, J, Childress, C, Sudol, M, Carey, DJ, Yang, W. (2010) HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates EGF-induced degradation of EGFR and ACK. Mol Cell Biol. 30(6):1541-1554. 2. Wang, J, Peng, Q, Lin, Q., Childress, C, Carey, DJ, Yang, W. (2010) Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition. J Biol Chem. 285(16):12279-12288. 3. Lin, Q., Zhu, F., Yang, W. (2009) Coupling cellular mitogenesis to apoptosis by designed bio-molecules. Cell Signal. 22:190-196. 4. Shen, F., Lin, Q., Gu, Y., Childress, C., Yang, W. (2007) Activated Cdc42-associated Kinase 1 (ACK1) Is a Component of EGF Receptor Signaling Complex and Regulates EGF Receptor Degradation. Mol Biol Cell. 18: 732-742. 5. Lin, Q., Yang, W., Baird, D., Feng, Q., Cerione, R.A. (2006) Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42. J Biol Chem. 281(46):35253-62. 6. Lin, Q., Yang, W., Cerione, R.A. (2006) Measurement of epidermal growth factor receptor turnover and effects of Cdc42. Methods in Enzymol. 406:614-25. 7. Qiong Lin, Reina N. Fuji, Wannian Yang, Richard A. Cerione (2003) RhoGDI Is Required for Cdc42-Mediated Cellular Transformation. Curr Biol. 13:1469-79. 8. Qiong Lin, Charles G. Lo, Richard A. Cerione, and Wannian Yang (2002) The Cdc42- target ACK2 interacts with SH3PX1 (sorting nexin 9) to regulate EGF receptor degradation. J Biol Chem. 277:10134-8. 9. Wannian Yang, Qiong Lin, Jihe Zhao, Jun-Lin Guan, Richard A. Cerione (2001) The nonreceptor tyrosine kinase ACK2, a specific target for Cdc42 and a negative regulator of cell growth and focal adhesion complexes. J Biol Chem. 276:43987-93. 10. Qiong Lin, Sarah E. Ruuska, Natacha S. Shaw, Diane Dong, and Noa Noy, 1999, Ligand selectivity of the peroxisome proliferator-activated receptor a. Biochemistry 38:185-190 11. Wannian Yang, Qiong Lin, Jun-Lin Guan, and Richard A. Cerione, 1999, activation of the Cdc42-associated tyrosine kinase 2 by cell adhesion via integrin b1. J. Biol. Chem. 274:8524-8530 12. Qiong Lin, Stephen J. Taylor, and David Shalloway, 1997, Specificity and determinants of Sam68 RNA binding: implications for the biological function of KH domains. J. Biol. Chem. 272 : 27274-27280. 13. Qiong Lin, Jurg Rohrer, R. Culter Allen, Mark Larche, Jeffrey M. Greene, Ann O. Shigeoka, Richard A. Gatti, D. Christian Derauf, John W. Belmont, and Mary Ellen Conley, 1996, A single strand conformation polymorphism study of CD40 ligand: efficient mutation analysis and carrier detection for X-linked hyper IgM syndrome. J. Clin. Invest. 97: 196-201 |