医学院 ENGLISH 江苏大学首页

师资队伍THE COLUMN

最新新闻

友情链接FRIENDLY LINK

当前位置 首页 >> 师资队伍 >> 教师风采 >> 正文

王佳

江苏大学,医学院,副教授          

 

教育经历:

2007/9 - 2010/12,东北师范大学,生物化学与分子生物学,博士

2004/9 - 2007/7,吉林大学,药理学,硕士

1997/9 - 2004/7,吉林大学,临床医学,学士

工作经历:

2016/6 -2017/6,南卫理公会大学,美国,神经生物学,博士后

2016/9- 至今,江苏大学,临床检验诊断学,副教授

2012/4 - 2015/12,江苏大学,临床检验诊断学,博士后

2011/6-2016/9 ,江苏大学,临床检验诊断学,讲师

2009/9-2010/7,明尼苏达大学,美国,神经生物学,访问学者

主持或参加科研项目

项目主持

2016-2018 江苏省高校自然科学基金(16KJB180005)白藜芦醇调控SIRT1

靶位基因抗抑郁机制的研究

2016-2019 江苏省重点研发计划(社会发展)E2016724基于SIRT1/PGC-1α

信号调控为基础的产褥期抑郁症干预研究

2013-2015 国家自然科学基金31201346人参多糖调控PGC-1α抗慢性疲劳综

合征的研究

2013-2015 中国博士后第52批面上项目2012M521019人参果胶调控

SIRT1/PGC-1α/PPARr信号通路发挥抗慢性疲劳综合症、抗抑郁症的

机制研究

2012-2014 江苏大学高级人才科研启动项目11JDG112人参果胶抗慢性疲劳

的活性成分及其分子机制

项目参与

1. 内嗅皮层GABA能神经元活动在精神分裂症样认知及感觉运动门控等功能障

碍中的作用和机制 国家自然科学基金面上项目81671053(第三)

2. 一种新的CD44剪切变异体与乳腺癌细胞耐药关系及其机制研究 国家自然基

81101677(第三)

3. 出生前后环境刺激因素对精神疾病脑功能障碍的影响及临床早期干预的应用

研究 江苏省临床医学专项BL2014068(第三)

4. 白藜芦醇调控SIRT1/PGC-1α信号通路抗抑郁机制的研究. 镇江市社会发展项

SH2015070(第二)

获奖及人才计划项目情况:

2017 镇江市科技进步三等奖 江苏大学 王佳,张维宁,许化溪。 HMGB1/PGC-1α等转录因子在神经精神与心血管疾病发生中的基础与临床研究

2016 江苏省第五期333高层次人才三层次培养对象

 

Scientific Research Publications:

Wang J, Crossly LST, D'Mello. Inhibiton of expression of FoxG1 and its association with HDAC3 in Huntington's disease. Experimental Biology and Medicine. (Being revised).

Chen SY, Liu YQ, Niu YY, Xu YH, Zhou QW, Xu XJ, Wang J*, Yu M*.2017. Increased abundance of myeloid-derived suppressor cells and Th17 cells in peripheral blood of newly-diagnosed Parkinson's disease patients. Neuroscience letter. 648: 21-25.

Wang J, Hosenie I, Allarakha A, Qian JJ, Chang XL, Li GH, Zhang WN. Depression: a comparative analysis of medical plants using chronic unpredictable mild stress as focal point. Biol. Pharm. Bull. (Being revised)

Su ZL, Ni P, Shen P, Liu YQ, Seidu AR, Xu WL, Zhu HT, Wang J*.2016. Bio-HMGB1 from breast cancer contributes to M-MDSC differentiation from bone marrow progenitor cells and facilitates conversion of  monocytes into MDSC-like cells. Cancer, Immunology, Immunotherapy. 66: 391.

Su ZL, Ni P, Zhou C, Wang J*. 2016. Myeloid-deprived suppressor cells in cancers and  inflammatory diseases: angel or demon? Scan J immunol. 84(5): 255-261.

Hosenie Irshad1, Wang J1, Allarakha Atiya, Zhang WN. 2016. Depression: Recent Insight into pathogenesis. IOSR Journal of Dental and Medical Science. 15(4) 109-114.

Wang, J, Bast T, Wang YC, Zhang WN. 2015. Hippocampus and two way active

avodidance conditioning: contrasting effects of cytotoxic lesion and temporary inactivation. Hippocampus. 25(12)1517-1531.

Wang J, Li GH, Xu Y, Zhang WN. 2015. Hyperactivity and disruption of prepulse inhibition induced by NMDA infusion of the rat ventral hippocampus: Comparision of uni- and bilateral stimulation. Neuroscience Letters. 594:150-154.

Wang J, Sun CX, Zheng Y, Pan HL, Zhou YF, Fan YY. 2014.The effective mechanism of the polysaccharides from Panax Ginseng on chronic fatigue syndrome. Arch. Pharm. Res. 37:530-538.

Hannah-Poquette C, Anderson GW, Flisher-Grinberg S, Wang J, Meinerding TM, Einat H. Modeling mania: Further validation for Black Swiss mice as model animals. Behav Brain Res. 2011 Sep 30;223(1):222-6.

Wang J, Flaisher-Grinberg S, Li SS, Liu HB, Sun L, Zhou YF, Einat H. 2010.

Antidepressant-like effects of the active acidic polysaccharide portion of ginseng in mice. Journal of Ethnopharmacology. 132: 65-69.

Wang, J, Li SS, Fan YY, Chen Y, Liu D, Cheng HR, Gao XG, Zhou Y.F. 2010. Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer. Journal of Ethnopharmacology. 130 (2): 421-423.

Fan YY, Cheng HR, Li SS, Wang J, Liu D, Hao M, Gao XG, et al. 2010 Relationship of the inhibition of cell migration with the structure of ginseng pectic polysaccharides. Carbohydrate Polymers. 81(2):340-347.

Cheng HR, Li SS, Fan YY, Gao XG, Hao M, Wang J, Zhang XY, Tai GH. Zhou YF. 2010. Comparative studies of the antiproliferative effects of ginseng polysaccharides on HT-29 human colon cancer cells. Medical Oncology, 28(1):175-181.

 

Conference:

Einat H, Flisher-Grinberg S, Hannah-Poquette C, Ashkenazy-Frolinger T, Katy K, Wang J, Anderson G. & Kronfeld-Schor, N. poster, Combining strategies to develop better animal models for bipolar disorder. Annual meeting of the International Behavioral Neuroscience Society, Sardinia, June 2010.

Wang, J., Sun, C.X., Chen, Y., Zhou, Y.F. The Research on the Anti-fatigue Activity of  Ginseng Polysaccharide . The proceedings for annual meeting of the Chinese society on the research and the application of the national polysaccharides. Jinan, Shandong, China, July 2008.

王佳,常宪鲁,钱进军,姜扬,王春艳,王玉聪,冯驰,王永洁,夏培慧,张颖,吴丹萍,张维宁。γ-氨基丁酸能神经元条件性敲除PGC-1α基因小鼠的制备。中华医学遗传学杂志。2017,34 (2): 200-204.

Hosenie Irshad,钱进军,张维宁,鲁京欣,王文欣,陈嘉欣,王春艳,査利晨,王佳*。人参果胶酸性组分调控BDNF/TrkB信号通路抗抑郁样行为的研究。时针国医国药2016,27(7): 6-8.

王佳,许燕,李国海,常宪鲁,周莹,张维宁*Poly I:C母体免疫刺激诱导的子代精神分裂症神经发育动物模型。心理科学。2015, 38 (1):229-236.

王佳,曲绍春,于晓风,周金影,睢大篔*"血瘀证"下急性心肌梗死模型与单纯急性心肌梗死模型大鼠心肌形态学、心肌酶学及血液流变学变化的比较。吉林大学学报(医学版)。2010, 36(1): 108-113.

Emailwangjiawork@163.com.

QQ: 626872150.