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张义全

张义全 简介

张义全(1985. 02~),男,安徽阜阳人,硕士生导师。2014年毕业于中国人民解放军军事医学科学院,军事预防医学系,获理学博士学位。现任职于江苏大学医学院医学生物化学系,主讲医学生物化学。主要从事病原细菌的致病机制研究。以第一作者或通讯作者,在Journal of BacteriologyBMC MicrobiologyFuture MicrobiologyOncotargetPLoS ONE等专业杂志上发表SCI论文20篇。另外,还是Frontiers in MicrobiologyPLoS ONECurrent Microbiology等杂志的审稿人。参编中文专著3部,英文专著1部。

联系方式

E-mailzhangyiquanq@163.com

主持的科研项目

1. 江苏省自然科学基金青年基金,BK20160505CalR调控副溶血弧菌VI型分泌系统的分子机制研究,2016/07-2019/0619万元,在研,主持

2. 国家自然科学基金青年基金81601809,副溶血弧菌ToxRIII分泌系统和耐热性直接溶血素的表达调控研究,2017/01-2019/1218万元,在研,主持

3. 国家自然科学基金面上项目分题31671290,副溶血弧菌毒力基因表达的密度感应调控机制,2017/01-2020/1221万元,在研,主持

4. 军事医学创新工程生物安全专题研究(重大项目)分题,副溶血弧菌致病性的分子调控机制研究,2017/10-2020/10110万元,在研,主持

5. 病原微生物生物安全国家重点实验室开放课题,SKLPBS1438,密度感应系统调控副溶血弧菌III型分泌系统的分子机制研究,2015/01-2016/1220万元,已结题,主持

6. 江苏大学科研启动基金资助项目,1291280020H-NS调控副溶血弧菌生物膜形成的分子机制研究,2015/01-2016/125万元,已结题,主持

近三年发表的主要SCI论文

1. Yiquan Zhang, He Gao, George Osei-Adjei, Ying Zhang, Wenhui Yang, Huiying Yang, Zhe Yin, Xinxiang Huang, Dongsheng Zhou. Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus. Frontiers in Microbiology, 2017, 8. (doi: 10.3389/fmicb.2017.02005)

2. George Osei-Adjei, He Gao, Ying Zhang, Lingyu Zhang, Wenhui Yang, Huiying Yang, Zhe Yin, Xinxiang Huang, Yiquan Zhang, Dongsheng Zhou. Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus. Oncotarget, 2017, 8(39): 65809-65822. (doi: 10.18632/oncotarget.19498) (Corresponding author)

3. He Gao, Lingyu Zhang, George Osei-Adjei, Wenhui Yang, Dongsheng Zhou, Xinxiang Huang, Huiying Yang, Zhe Yin, Yiquan Zhang. Transcriptional regulation of cpsQ-mfpABC and mfpABC by CalR in Vibrio parahaemolyticus. MicrobiologyOpen, 2017, 6(4): e470. (doi: 10.1002/mbo3.470) (Corresponding author)

4. Lingyu Zhang, George Osei-Adjei, Ying Zhang, He Gao, Wenhui Yang, Dongsheng Zhou, Xinxiang Huang, Huiying Yang, Yiquan Zhang. CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells. Archives of Microbiology, 2017, 199(6):931-938. (doi: 10.1007/s00203-017-1361-6) (Corresponding author)

5. Yiquan Zhang, Ying Zhang, He Gao, Lingyu Zhang, Zhe Yin, Xinxiang Huang, Dongsheng Zhou, Huiying Yang, Wenhui Yang, Li Wang. Vibrio parahaemolyticus CalR down regulates the thermostable direct hemolysin (TDH) gene transcription and thereby inhibits hemolytic activity. Gene, 2017, 613: 39-44. ( doi: 10.1016/j.gene.2017.03.001)

6. Renfei Lu, George Osei-Adjei, Xinxiang Huang, Yiquan Zhang. Role and regulation of the orphan AphA protein of quorum sensing in pathogenic Vibrios. Future Microbiology, 2017, accepted: 29 September 2017. (Corresponding author)

7. Yiquan Zhang, George Osei-Adjei, Bin Ni, Haihong Fang, Lingyu Zhang, Xin Zhao, Xinxiang Huang, Huiying Yang, Wenhui Yang, Fengjun Sun. Transcription of exsD is repressed directly by H-NS in Vibrio parahaemolyticus. Microbial Pathogenesis, 2016, 97: 221-5. (doi: 10.1016/j.micpath)

8. Yiquan Zhang, Lingyu Zhang, Shuning Hou, Xinxiang Huang, Fengjun Sun, He Gao. The master quorum-sensing regulator OpaR is activated indirectly by H-NS in Vibrio parahaemolyticus. Current Microbiology, 2016, 73 (1): 71-6. (doi:10.1007/s00284-016-1018-8)

9. Yiquan Zhang, Fengjun Sun, Huiying Yang, Lei Liu, Bin Ni, Xinxiang Huang, Ruifu Yang, Dongsheng Zhou. Current Microbiology, 2015, 70 (3): 398-403. (doi: 10.1007/s00284-014-0736-z)