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张盈

个人简介

张盈,女,198506月出生,讲师,硕士生导师。

【联系方式】

E-mail: zhangyingzj85@163.com

【学术简介】

学习经历

2003.09-2007.06 南京理工大学生物工程专业,获学士学位;

2007.09-2012.06 南京理工大学分子代谢中心,获博士学位;

工作经历:

2012.06-至今 江苏大学医学院,讲师。

【主讲课程】

医学生物化学,MBBS国际班生物化学与分子生物学。

【研究领域】

病原菌伤寒沙门菌致病机制研究

【主持科研项目】

江苏大学高级专业人才科研启动基金,伤寒沙门菌sRNA1068的功能及分子机制研究(13JDG026),2013.06-2016.06,主持。

江苏省自然科学基金青年基金,伤寒沙门菌sRNA1068的作用及分子机制研究(BK20130504),2013.07-2016.06,结题。

国家自然科学基金青年基金,malS-5'UTR调节伤寒沙门菌耐酸力和侵袭力的作用机制研究(31400125),2015.01-2017.12,主持。

【发表论文】

1. Zhang Y, Wang Z, Zhao Y, Zhao M, Wang S, Hua Z, Zhang J. The plasma 5'-AMP acts as a potential upstream regulator of hyperglycemia in type 2 diabetic mice. Am J Physiol Endocrinol Metab, 2012, 302(3):E325-333.

2. Zhang Y, Xia L, Pang W, Wang T, Chen P, Zhu B, Zhang J. A novel soluble β-1, 3-D-glucan Salecan reduces adiposity and improves glucose tolerance in high-fat diet-fed mice. Br J Nutr, 2013, 109(2):254-262.

3. Zhang Y, Yan D, Xia L, Zhao X, Osei-Adjei G, Xu S, Sheng X, Huang X. The malS-5'UTR regulates hisG, a key gene in the histidine biosynthetic pathway in Salmonella enterica serovar Typhi. Can J Microbiol. 2017, 63(4): 287-295.

4. Pang W#, Zhang Y#, Wang S, Jia A, Dong W, Cai C, Hua Z, Zhang J. The mPlrp2 and mClps genes are involved in the hydrolysis of retinyl esters in the mouse liver. J Lipid Res, 2011, 52(5):934-941. (共同第一作者)

5. Zhang Q#, Zhang Y#, Zhang X#, Zhan L, Zhao X, Xu S, Sheng X, Huang X. The novel cis-encoded antisense RNA AsrC positively regulates the expression of rpoE-rseABC operon and thus enhances the motility of Salmonella enterica serovar typhi. Front Microbiol. 2015, 6:990. (共同第一作者)

6. 张盈,夏琳,逄文强,王涛,张建法. 腺苷酸激酶与AMP信号在感知及维持机体能量中的作用. 生命科学,2011, 23(5):434-439.

7. Zhang Y, Zhang Y, Gao H, Zhang L, Yin Z, Huang X, Zhou D, Yang H, Yang W, Wang L. Vibrio parahaemolyticus CalR down regulates the thermostable direct hemolysin (TDH) gene transcription and thereby inhibits hemolytic activity. Gene. 2017, 613:39-44.

8. Xia L, Wang Z, Zhang Y, Yang X, Zhan Y, Cheng R, Wang S, Zhang J. Reciprocal regulation of insulin and plasma 5-AMP in glucose homeostasis in mice. Journal of Endocrinology, 2015, 224: 225-234.

9. Xia L, Ma S, Zhang Y, Wang T, Zhou M, Wang Z, Zhang J. Daily variation in global and local DNA methylation in mouse livers. PLoS One, 2015, 10: e0118101.

10. Ji Y, Li W, Zhang Y, Chen L, Zhang Y, Zheng X, Huang X, Ni B. QseB mediates biofilm formation and invasion in Salmonella enterica serovar Typhi. Microb Pathog. 2017, 104:6-11.

11. Zhang L, Osei-Adjei G, Zhang Y, Gao H, Yang W, Zhou D, Huang X, Yang H, Zhang Y. CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells. Arch Microbiol. 2017, 199(6):931-938.

12. Gong M, Xu S, Jin Y, Zhang Y, Dadzie I, Zhang X, Wang Z, Zhu Y, Ni B, Sheng X, Huang X. 5'-UTR of malS increases the invasive capacity of Salmonella enterica serovar Typhi by influencing the expression of bax. Future Microbiol. 2015, 10:941-954.

13. Osei-Adjei G, Gao H, Zhang Y, Zhang L, Yang W, Yang H, Yin Z, Huang X, Zhang Y, Zhou D. Regulatory actions of ToxR and CalR on their own genes and type III secretion system 1 in Vibrio parahaemolyticus. Oncotarget. 2017, 8:65809-65822.

14. Dadzie I, Ni B, Gong M, Zhang Y, Zhang H, Sheng X, Xu S, Huang X. Identification and characterization of a cis antisense RNA of the parC gene encoding DNA topoisomerase IV of Salmonella enterica serovar Typhi. Res Microbiol, 2014, 165(6):439-446.